Insulin-like growth factor II stimulates motor nerve regeneration.

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Insulin-like growth factor II stimulates motor nerve regeneration.

Injury to mammalian motor nerves can lead to paralysis, but relatively successful regeneration may occur when conditions are favorable. Elucidation of the mechanism upholding successful regeneration is of theoretical and clinical interest. In this study, the hypothesis that insulin-like growth factor II (IGF-II) can stimulate motor nerve regeneration was tested. When IGF-II was infused continuo...

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Insulin, insulin-like growth factor II, and nerve growth factor effects on tubulin mRNA levels and neurite formation.

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1992

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.89.24.11716